Reduced expression of IFIH1 is protective for type 1 diabetes.

Autor Kate Downes, Marcin Pekalski, Karen L Angus, Matthew Hardy, Sarah Nutland, Deborah J Smyth, Neil M Walker, Chris Wallace, John A Todd
Vydáno 2010-09-01

The PTPN22 locus and rheumatoid arthritis: no evidence for an effect on risk independent of Arg620Trp.

Autor Wan R Wan Taib, Deborah J Smyth, Marilyn E Merriman, Nicola Dalbeth, Peter J Gow, Andrew A Harrison, John Highton, Peter B B Jones, Lisa Stamp, Sophia Steer, John A Todd, Tony R Merriman
Vydáno 2010-10-01

Immune disease variants modulate gene expression in regulatory CD4+ T cells

Autor Lara Bossini-Castillo, Dafni A. Glinos, Natalia Kunowska, Gosia Golda, Abigail A. Lamikanra, Michaela Spitzer, Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Claire Cattermole, Kaur Alasoo, Alice Mann, Kousik Kundu, Anna Lorenc, Nicole Soranzo, Ian Dunham, David J. Roberts, Gosia Trynka
Vydáno 2022-04-01

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.

Autor Ricardo C Ferreira, Daniel F Freitag, Antony J Cutler, Joanna M M Howson, Daniel B Rainbow, Deborah J Smyth, Stephen Kaptoge, Pamela Clarke, Charlotte Boreham, Richard M Coulson, Marcin L Pekalski, Wei-Min Chen, Suna Onengut-Gumuscu, Stephen S Rich, Adam S Butterworth, Anders Malarstig, John Danesh, John A Todd
Vydáno 2013-04-01