نتائج البحث - David Brough

Digital interventions for supporting alcohol abstinence in aftercare – a systematic review حسب Luana Lenzi, Aaliya Ibrahim, David Brough, Alexander Thompson

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Inhibiting the NLRP3 Inflammasome حسب Lina Y. El-Sharkawy, David Brough, Sally Freeman

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Pyroptosis leads to loss of centrosomal integrity in macrophages حسب Siyi Bai, Fatima Martin-Sanchez, David Brough, Gloria Lopez-Castejon

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Inhibition of calpain blocks the phagosomal escape of Listeria monocytogenes. حسب Gloria Lopez-Castejon, David Corbett, Marie Goldrick, Ian S Roberts, David Brough

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Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular barrier function... حسب Janet Storm, Grazia Camarda, Michael J Haley, David Brough, Kevin N Couper, Alister G Craig

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The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome حسب Tara A. Gleeson, Christina Kaiser, Catherine B. Lawrence, David Brough, Stuart M. Allan, Jack P. Green

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Differential Impacts of Components of Particulate Matter on Epithelial Cell Toxicity and Immune Responses حسب George Adams, Oliver Wagstaff, Dave Topping, David Brough, Gloria Lopez-Castejon, Riccardo D’Elia, Sheena M. Cruickshank

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Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium حسب Paula I. Seoane, James A. Beswick, Andrew G. Leach, Tessa Swanton, Lucy V. Morris, Kevin Couper, Martin Lowe, Sally Freeman, David Brough

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Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria حسب Michael J. Haley, Ruben Barroso, Dhifaf A. Jasim, Megan Haigh, Jack Green, Ben Dickie, Alister G. Craig, David Brough, Kevin N. Couper

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Inflammatory responses following CRISPR modification of the nuclear localisation sequence in endogenous interleukin-1 alpha حسب Christopher Hoyle, Rodrigo Díaz Pino, Si Min Lai, Jack P. Green, Antony Adamson, Graham Coutts, Catherine B. Lawrence, Mark Travis, David Brough, Gloria Lopez-Castejon

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Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhage حسب Jack Barrington, Jack Rivers-Auty, Patrick Strangward, Sabrina Tamburrano, Nikolett Lénárt, Tessa Swanton, Eloise Lemarchand, Adrian R. Parry-Jones, Ádám Dénes, David Brough, Stuart M. Allan

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Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions حسب Rose Wellens, Victor S. Tapia, Paula I. Seoane, Hayley Bennett, Antony Adamson, Graham Coutts, Jack Rivers-Auty, Martin Lowe, Jack P. Green, Gloria Lopez-Castejon, David Brough, Christopher Hoyle

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The tumour immune microenvironment is enriched but suppressed in vestibular schwannoma compared to meningioma: therapeutic implications for NF2-related schwannomatosis حسب Grace E. Gregory, Michael J. Haley, Adam Paul Jones, Leo A. H. Zeef, D. Gareth Evans, Andrew T. King, Pawel Paszek, Kevin N. Couper, David Brough, Omar N. Pathmanaban

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Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation حسب Xenia Kodji, Zizheng Kee, Robyn McKenna, Joao de Sousa Valente, Harriet Ravenscroft, Hayley McMillan, John Gamble, Yvonne Dombrowski, Paul Moynagh, David Brough, Fionnuala T. Lundy, Susan D. Brain, Ikhlas A. El Karim

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Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA حسب Helen Parker, Stuart M Ellison, Rebecca J Holley, Claire O'Leary, Aiyin Liao, Jalal Asadi, Emily Glover, Arunabha Ghosh, Simon Jones, Fiona L Wilkinson, David Brough, Emmanuel Pinteaux, Hervé Boutin, Brian W Bigger

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Brazilin is a natural product inhibitor of the NLRP3 inflammasome حسب Emily McMahon, Sherihan El-Sayed, Jack Green, Christopher Hoyle, Lorna FitzPatrick, Emma V. Jones, Eve Corrie, Rebecca L. Kelly, Mairi Challinor, Sally Freeman, Richard A. Bryce, Catherine B. Lawrence, David Brough, Paul R. Kasher

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Spatial mapping of immune cell environments in NF2-related schwannomatosis vestibular schwannoma حسب Adam P. Jones, Michael J. Haley, Miriam H. Meadows, Grace E. Gregory, Cathal J. Hannan, Ana K. Simmons, Leoma D. Bere, Daniel G. Lewis, Pedro Oliveira, Miriam J. Smith, Andrew T. King, D. Gareth R. Evans, Pawel Paszek, David Brough, Omar N. Pathmanaban, Kevin N. Couper

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