Resultats de la cerca - David A Sinclair

Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice per Golam Mezbah Uddin, Neil A Youngson, David A Sinclair, David A Sinclair, Margaret J Morris

Obtenir text complet

Turning back time: a comprehensive list of interventions that decrease next-generation epigenetic aging clocks in humans per Adiv A. Johnson, David A. Sinclair

Obtenir text complet

Can artificial intelligence identify effective COVID‐19 therapies? per Michael B Schultz, Daniel Vera, David A Sinclair

Obtenir text complet

MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. per Oliver Medvedik, Dudley W Lamming, Keyman D Kim, David A Sinclair

Obtenir text complet

Correction: nicotinamide impairs entry into and exit from meiosis I in mouse oocytes. per Angelique Riepsamen, Lindsay Wu, Laurin Lau, Dave Listijono, William Ledger, David A Sinclair, Hayden Homer

Obtenir text complet

Novel feature selection methods for construction of accurate epigenetic clocks. per Adam Li, Amber Mueller, Brad English, Anthony Arena, Daniel Vera, Alice E Kane, David A Sinclair

Obtenir text complet

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers per Golam M. Uddin, Neil A. Youngson, Sabiha S. Chowdhury, Christopher Hagan, David A. Sinclair, Margaret J. Morris

Obtenir text complet

The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice per Qing-Shuo Zhang, Matthew Deater, Kathryn Schubert, Laura Marquez-Loza, Carl Pelz, David A. Sinclair, Markus Grompe

Obtenir text complet

Sex dimorphism and tissue specificity of gene expression changes in aging mice per Dantong Zhu, Matt Arnold, Brady A. Samuelson, Judy Z. Wu, Amber Mueller, David A. Sinclair, Alice E. Kane

Obtenir text complet

Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung per Pierre Montay-Gruel, Yafeng Zhu, Benoit Petit, Ron Leavitt, Mike Warn, Erich Giedzinski, Jonathan Ollivier, David A. Sinclair, Marie-Catherine Vozenin, Charles L. Limoli

Obtenir text complet

Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila per Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon

Obtenir text complet

Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells per Pauline Rimmelé, Carolina L. Bigarella, Raymond Liang, Brigitte Izac, Rebeca Dieguez-Gonzalez, Gaetan Barbet, Michael Donovan, Carlo Brugnara, Julie M. Blander, David A. Sinclair, Saghi Ghaffari

Obtenir text complet

Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty per Michael B. Schultz, Alice E. Kane, Sarah J. Mitchell, Michael R. MacArthur, Elisa Warner, David S. Vogel, James R. Mitchell, Susan E. Howlett, Michael S. Bonkowski, David A. Sinclair

Obtenir text complet

Age and life expectancy clocks based on machine learning analysis of mouse frailty per Michael B. Schultz, Alice E. Kane, Sarah J. Mitchell, Michael R. MacArthur, Elisa Warner, David S. Vogel, James R. Mitchell, Susan E. Howlett, Michael S. Bonkowski, David A. Sinclair

Obtenir text complet

NMN Supplementation Rescues Fertility and Bone Strength in Chemotherapy-Treated Mice per Maria B. MARINOVA, Wing-Hong Jonathan HO, Michael J. BERTOLDO, Vedran LOVRIC, Kaisa SELESNIEMI, William R. WALSH, David A. SINCLAIR, Kirsty WALTERS, Robert B. GILCHRIST, Lindsay E. WU

Obtenir text complet

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks per Michael Van Meter, Matthew Simon, Gregory Tombline, Alfred May, Timothy D. Morello, Basil P. Hubbard, Katie Bredbenner, Rosa Park, David A. Sinclair, Vilhelm A. Bohr, Vera Gorbunova, Andrei Seluanov

Obtenir text complet

Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy. per Shaday Michan, Aimee M Juan, Christian G Hurst, Zhenghao Cui, Lucy P Evans, Colman J Hatton, Dorothy T Pei, Meihua Ju, David A Sinclair, Lois E H Smith, Jing Chen

Obtenir text complet

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. per Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair

Obtenir text complet

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic... per Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari

Obtenir text complet

Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography per Juan A. Martínez‐Greene, Karina Hernández‐Ortega, Ricardo Quiroz‐Baez, Osbaldo Resendis‐Antonio, Israel Pichardo‐Casas, David A. Sinclair, Bogdan Budnik, Alfredo Hidalgo‐Miranda, Eileen Uribe‐Querol, María del Pilar Ramos‐Godínez, Eduardo Martínez‐Martínez

Obtenir text complet