Resultados da pesquisa - Daniel Hubschmann

simplifyEnrichment: A Bioconductor Package for Clustering and Visualizing Functional Enrichment Results Por Zuguang Gu, Daniel Hübschmann

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P438: INTRACELLULAR CITRATE LEVELS MODULATE ANTI-APOPTOTIC PROTEINS TO ENHANCE VENETOCLAX SENSITIVITY IN ACUTE MYELOID LEUKEMIA STEM CELLS Por Aykut Demir, Alireza Pouya, Maximilian Mönnig, Gernot Poschet, Carolin Andresen, Daniel Hübschmann, Nicola Zamboni, Carsten Müller-Tidow, Simon Raffel

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Multimodal plasma and urinary cell-free DNA profiling improves risk stratification in newly diagnosed prostate cancer Por Anja Lisa Riediger, Samaneh Eickelschulte, Florian Janke, Daniela Janscho, Olga Lazareva, Daniel Hübschmann, Stefan Duensing, Oliver Stegle, Holger Sültmann, Magdalena Görtz

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Monitoring soluble cMET and ctDNA in metastatic uveal melanoma patients to track early disease progression on immunotherapies Por Devayani Machiraju, Christian H Ziener, Elena Clementi, Francisco García-Asencio, Jennifer Hüllein, Jasmin Richter, Bénédicte Lenoir, Melanie Wiecken, Daniel Hübschmann, Dirk Jäger, Jessica C Hassel

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Precision oncology for advanced-stage adenocarcinoma of the appendix: comprehensive molecular characterisation identifies actionable lesions and potential predictive biomarkers Por Moritz Jesinghaus, Albrecht Stenzinger, Simon Kreutzfeldt, Christoph Heining, Hanno Glimm, Stefan Fröhling, Lena Weiss, Anna Melissa Schlitter, Sebastian Lange, Christoph Benedikt Westphalen, Nicole Pfarr, Hannah Lisiecki, Daniel Hübschmann

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Compartment-Specific NK Cell Phenotypes Reveal Distinct Maturation and Activation States in Inflammatory Arthritis Por Franca Sophie Deicher, Tarik Exner, Maren Claus, Schayan Yousefian, Lea Rodon, Sophie Elisabeth Leonhardt, Jörg H.W. Distler, Carsten Watzl, Hanns-Martin Lorenz, Simon Haas, Daniel Hübschmann, Wolfgang Merkt

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Last Resort? Rationale for Comprehensive Molecular Analysis in Treatment-Refractory R/M HNSCC: A Case Report of Remarkable Response to Sacituzumab Govitecan Following Molecular and... Por Henrike Barbara Zech, Philippe Schafhausen, Leonie Ramke, Janna-Lisa Velthaus, Simon Kreutzfeldt, Daniel Hübschmann, Kai Rothkamm, Carsten Bokemeyer, Anna Sophie Hoffmann, Stefan Fröhling, Hanno Glimm, Christian Stephan Betz, Malte Kriegs, Maximilian Christopeit

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An AI-based segmentation and analysis pipeline for high-field MR monitoring of cerebral organoids Por Luca Deininger, Sabine Jung-Klawitter, Ralf Mikut, Petra Richter, Manuel Fischer, Kianush Karimian-Jazi, Michael O. Breckwoldt, Martin Bendszus, Sabine Heiland, Jens Kleesiek, Thomas Opladen, Oya Kuseyri Hübschmann, Daniel Hübschmann, Daniel Schwarz

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PB1759: RETAINED FUNCTIONAL NORMAL AND/OR PRE-LEUKEMIC HSCS IN THE BONE MARROW ARE ASSOCIATED TO GOOD PROGNOSIS IN DNMT3AMUTNPM1MUT AML PATIENTS Por Elisa Donato, Nadia Correia, Carolin Andresen, Darja Karpova, Roberto Würth, Corinna Klein, Markus Sohn, Adriana Przybylla, Petra Zeisberger, Kathrin Rothfelder, Helmut Salih, Halvard Bonig, Sebastian Stasik, Christoph Röllig, Anna Dolnik, Lars Bullinger, Frank Buchholz, Christian Thiede, Daniel Hübschmann, Andreas Trumpp

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Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials Por Federico Nichetti, Jennifer Hüllein, Pauline du Rusquec, Erin Pleasance, Li Chen, Andreas Mock, Peter Horak, Paolo Ambrosini, Simone Rota, Monica Niger, Luca Agnelli, Gabriele Tinè, Dominic Edelmann, Christophe Le Tourneau, Janessa Laskin, Giancarlo Pruneri, Chi Wang, Daniel Hübschmann, Filippo de Braud, Stefan Fröhling, Luigi Mariani

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Rationale and design of the PAMSARC (pasireotide as maintenance treatment with monthly deep intramuscular injection in SSTR2/3/5-expressing synovial sarcoma and desmoplastic small... Por Christoph E. Heilig, Christoph Heining, Editha Gnutzmann, Sandra Roldan, Laura Heiligenthal, Monika Sparber-Sauer, Dennis Hahn, Uta Dirksen, Rainer Hamacher, Anne Flörcken, Anne Thorwarth, Christoph K.W. Deinzer, Verena I. Gaidzik, Elke Pfaff, Daniel Hübschmann, Karin Arndt, Stefan M. Pfister, Hanno Glimm, Stefan Fröhling, Richard F. Schlenk

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P1218: A REPROGRAMMING OF THE LYMPH NODE MICROENVIRONMENT UNDERLIES LOSS OF COMPARTMENTALISATION IN AGGRESSIVE LYMPHOMAS Por Anna Mathioudaki, Felix Czernilofsky, Lea Jopp-Saile, Raphael Lutz, Dominik Vonflicht, XI Wang, Marc-A. Baertsch, Harald Vohringer, Tobias Roider, Johannes Mammen, Diana Ordonez-Rueda, Caroline Pabst, Wolfgang Huber, Andreas Trumpp, Carsten Müller-Tidow, Gary P. Nolan, Vladimir Benes, Judith B. Zaugg, Daniel Hübschmann, Simon Haas, Sascha Dietrich

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Glucocorticoids induce a phagocytic C1Q+ macrophage phenotype primed for IFNγ-dependent CXCL9 secretion Por Alexandra S. Triebig, Tanja Maier, Paul Schwarzlmueller, Sena Atici, Martin E. Kirmaier, Vasileios Chortis, Kleiton S. Borges, David T. Breault, Claudio Ribeiro, Adrian Gottschlich, Laura-Sophie Landwehr, Nicole Bechmann, Mirko Peitzsch, Nagarajan Paramasivam, Sebastian Theurich, Stefan Fröhling, Hanno Glimm, Daniel Hübschmann, Martin Fassnacht, Martin Reincke, Jose Pedro Friedmann-Angeli, Isabel Weigand, Matthias Kroiss

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The Knowledge Connector decision support system for multiomics-based precision oncology Por Daniel Hübschmann, Simon Kreutzfeldt, Benjamin Roth, Katrin Glocker, Janine Schoop, Lena Oeser, Steffen Hausmann, Christian Koch, Sebastian Uhrig, Jennifer Hüllein, Barbara Hutter, Martina Fröhlich, Christoph E. Heilig, Maria-Veronica Teleanu, Daniel B. Lipka, Irina A. Kerle, Annika Baude-Müller, Katja Beck, Christoph Heining, Hanno Glimm, Frank Ückert, Alexander Knurr, Stefan Fröhling, Peter Horak

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Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology Por Irina A. Kerle, Thomas Gross, Anja Kögler, Jonas S. Arnold, Maximilian Werner, Jan-Niklas Eckardt, Elena E. Möhrmann, Marie Arlt, Barbara Hutter, Jennifer Hüllein, Daniela Richter, Martin M. K. Schneider, Mario Hlevnjak, Lino Möhrmann, Dorothea Hanf, Christoph E. Heilig, Simon Kreutzfeldt, Maria-Veronica Teleanu, Evelin Schröck, Daniel Hübschmann, Peter Horak, Christoph Heining, Stefan Fröhling, Hanno Glimm

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A macrophage-predominant immunosuppressive microenvironment and therapeutic vulnerabilities in advanced salivary gland cancer Por Erika Zuljan, Benjamin von der Emde, Iris Piwonski, Ana Pestana, Konrad Klinghammer, Andreas Mock, Peter Horak, Christoph Heining, Frederick Klauschen, Ina Pretzell, Melanie Boerries, Christian H. Brandts, Simon Kreutzfeldt, Maria-Veronica Teleanu, Daniel Hübschmann, Luc G. T. Morris, Max Heiland, Ulrich Keller, Thomas Conrad, Hanno Glimm, Stefan Fröhling, Sebastian Ochsenreither, Ulrich Keilholz, Eric Blanc, Dieter Beule, Damian T. Rieke

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Molecular Characterization and Clinical Relevance of MGMT‐Silenced Pancreatic Cancer Por Federico Nichetti, Marco Silvestri, Luca Agnelli, Andrea Franza, Chiara Pircher, Simone Rota, Paolo Ambrosini, Giuseppe Fotia, Jennifer Hüllein, Giovanni Randon, Panna Lajer, Federica Perrone, Elena Tamborini, Giuseppe Leoncini, Jorgelina Coppa, Michele Droz Dit Busset, Sara Pusceddu, Massimo Milione, Federica Morano, Filippo Pietrantonio, Giancarlo Pruneri, Vincenzo Mazzaferro, Daniel B. Lipka, Bruno Christian Köhler, Daniel Hübschmann, Stefan Fröhling, Filippo deBraud, Monica Niger

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Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions Por Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav D. Diwan, Zunamys I. Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Dominic Helm, Martin Schneider, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert B. Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl

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Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy Por Raphael Lutz, Florian Grünschläger, Malte Simon, Mohamed H. S. Awwad, Marcus Bauer, Schayan Yousefian, Niklas Beumer, Lea Jopp-Saile, Anastasia Sedlmeier, Llorenç Solé-Boldo, Bogdan Avanesyan, Dominik Vonficht, Patrick Stelmach, Georg Steinbuss, Tobias Boch, Simon Steiger, Marc-Andrea Baertsch, Nina Prokoph, Karsten Rippe, Brian G. M. Durie, Claudia Wickenhauser, Andreas Trumpp, Carsten Müller-Tidow, Daniel Hübschmann, Niels Weinhold, Marc S. Raab, Benedikt Brors, Hartmut Goldschmidt, Charles D. Imbusch, Michael Hundemer, Simon Haas

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MGMT inactivation as a new biomarker in patients with advanced biliary tract cancers Por Monica Niger, Federico Nichetti, Andrea Casadei‐Gardini, Federica Morano, Chiara Pircher, Elena Tamborini, Federica Perrone, Matteo Canale, Daniel B. Lipka, Andrea Vingiani, Luca Agnelli, Anna Dobberkau, Jennifer Hüllein, Felix Korell, Christoph E. Heilig, Sara Pusceddu, Francesca Corti, Michele Droz, Paola Ulivi, Michele Prisciandaro, Maria Antista, Marta Bini, Laura Cattaneo, Massimo Milione, Hanno Glimm, Bruno C. Köhler, Giancarlo Pruneri, Daniel Hübschmann, Stefan Fröhling, Vincenzo Mazzaferro, Filippo Pietrantonio, Maria Di Bartolomeo, Filippo deBraud

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