BRAF BRAF V600E Cushing’s disease RAS mutation RET/PTC rearrangements SUV PET/CT adjuvant treatment adrenal adenomas adrenal cortex adrenal tumors adrenocortical cancer aggressive PitNET aggressive pituitary adenoma aggressive pituitary tumor angiogenesis bic Book Industry Communication::M Medicine carcinoma differentiated thyroid cancer focus group interview gene expression hyaluronan synthase 1 immune checkpoint inhibitors (ICIs) information needs and preferences intratumoral heterogeneity ipilimumab ki-67 lenvatinib mitotane molecular clusters multikinase inhibitors