Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

Yazar: Jan Glaser, Uta Schurigt, Brian M. Suzuki, Conor R. Caffrey, Ulrike Holzgrabe
Baskı/Yayın Bilgisi 2015-06-01

Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor.

Yazar: Maha-Hamadien Abdulla, Kee-Chong Lim, Mohammed Sajid, James H McKerrow, Conor R Caffrey
Baskı/Yayın Bilgisi 2007-01-01

Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis.

Yazar: Liliana Rojo-Arreola, Thavy Long, Dan Asarnow, Brian M Suzuki, Rahul Singh, Conor R Caffrey
Baskı/Yayın Bilgisi 2014-01-01

Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystati...

Yazar: Hana Dvořáková, Roman Leontovyč, Tomáš Macháček, Anthony J. O'Donoghue, Ondřej Šedo, Zbyněk Zdráhal, Charles S. Craik, Conor R. Caffrey, Petr Horák, Libor Mikeš
Baskı/Yayın Bilgisi 2020-02-01

TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling

Yazar: Alan R. Wolfe, R. Jeffrey Neitz, Mark Burlingame, Brian M. Suzuki, KC Lim, Mark Scheideler, David L. Nelson, Leslie Z. Benet, Conor R. Caffrey
Baskı/Yayın Bilgisi 2018-12-01

Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty

Yazar: Snigdha Singh, Nelly El-Sakkary, Danielle E. Skinner, Prem Prakash Sharma, Sabine Ottilie, Yevgeniya Antonova-Koch, Prashant Kumar, Elizabeth Winzeler, Poonam, Conor R. Caffrey, Brijesh Rathi
Baskı/Yayın Bilgisi 2020-02-01

Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica.

Yazar: Ileana Corvo, Anthony J O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Alegra Eroy-Reveles, Leda Roche, James H McKerrow, John P Dalton, Charles S Craik, Conor R Caffrey, José F Tort
Baskı/Yayın Bilgisi 2013-01-01

Biomechanical interactions of Schistosoma mansoni eggs with vascular endothelial cells facilitate egg extravasation.

Yazar: Yi-Ting Yeh, Danielle E Skinner, Ernesto Criado-Hidalgo, Natalie Shee Chen, Antoni Garcia-De Herreros, Nelly El-Sakkary, Lawrence Liu, Shun Zhang, Adithan Kandasamy, Shu Chien, Juan C Lasheras, Juan C Del Álamo, Conor R Caffrey
Baskı/Yayın Bilgisi 2022-03-01