Mimicking the Tumor Microenvironment to Regulate Macrophage Phenotype and Assessing Chemotherapeutic Efficacy in Embedded Cancer Cell/Macrophage Spheroid Models

di Tevis, Kristie M., Cecchi, Ryan J., Colson, Yolonda L., Grinstaff, Mark W.
Pubblicato in Acta Biomater (2016)

Precise Cas9 targeting enables genomic mutation prevention

di Chavez, Alejandro, Pruitt, Benjamin W., Tuttle, Marcelle, Shapiro, Rebecca S., Cecchi, Ryan J., Winston, Jordan, Turczyk, Brian M., Tung, Michael, Collins, James J., Church, George M.
Pubblicato in Proc Natl Acad Sci U S A (2018)

Comparative Analysis of Cas9 Activators Across Multiple Species

di Chavez, Alejandro, Tuttle, Marcelle, Pruitt, Benjamin W, Ewen-Campen, Ben, Chari, Raj, Ter-Ovanesyan, Dmitry, Haque, Sabina J, Cecchi, Ryan J, Kowal, Emma J K, Buchthal, Joanna, Housden, Benjamin E, Perrimon, Norbert, Collins, James J, Church, George
Pubblicato in Nat Methods (2016)

An enhanced CRISPR repressor for targeted mammalian gene regulation

di Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T, Davidsohn, Noah, Ebrahimkhani, Mo R., Collins, James J., Lewis, Nathan E., Kiani, Samira, Church, George M.
Pubblicato in Nat Methods (2018)