ATPS-55 INFLUENCE OF MAPK AND PI3K PATHWAY MUTATIONS ON RESPONSE TO TARGETED INHIBITORS

по McNeill, Robert S., Canoutas, Demitra A., Schmid, Ralf S., Bash, Ryan E., Constance, Brian H., Azam, Salma H., Reuther, Rachel A., Johnson, Gary L., Miller, C. Ryan
Опубликовано в: Neuro Oncol (2015)

PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition

по McNeill, Robert S., Stroobant, Emily E., Smithberger, Erin, Canoutas, Demitra A., Butler, Madison K., Shelton, Abigail K., Patel, Shrey D., Limas, Juanita C., Skinner, Kasey R., Bash, Ryan E., Schmid, Ralf S., Miller, C. Ryan
Опубликовано в: PLoS One (2018)

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma

по McNeill, Robert S, Canoutas, Demitra A, Stuhlmiller, Timothy J, Dhruv, Harshil D, Irvin, David M, Bash, Ryan E, Angus, Steven P, Herring, Laura E, Simon, Jeremy M, Skinner, Kasey R, Limas, Juanita C, Chen, Xin, Schmid, Ralf S, Siegel, Marni B, Van Swearingen, Amanda E D, Hadler, Michael J, Sulman, Erik P, Sarkaria, Jann N, Anders, Carey K, Graves, Lee M, Berens, Michael E, Johnson, Gary L, Miller, C Ryan
Опубликовано в: Neuro Oncol (2017)