Sökresultat - Cameron J Turtle

The impact of the large B-cell lymphoma tumor microenvironment on efficacy of CD19-directed CAR-T immunotherapy av Helen P. Cashman, Cameron J. Turtle, Cameron J. Turtle, Cameron J. Turtle

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PD‐L1+ macrophage and tumor cell abundance and proximity to T cells in the pretreatment large B‐cell lymphoma microenvironment impact CD19 CAR‐T cell immunotherapy efficacy av Alexandre V. Hirayama, Jocelyn H. Wright, Kimberly S. Smythe, Salvatore Fiorenza, Akira N. Shaw, Jordan Gauthier, David G. Maloney, Kikkeri N. Naresh, Cecilia C. S. Yeung, Cameron J. Turtle

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Targeting the membrane-proximal C2-set domain of CD33 for improved CAR T cell therapy av Salvatore Fiorenza, Sheryl Y.T. Lim, George S. Laszlo, Erik L. Kimble, Tinh-Doan Phi, Margaret C. Lunn-Halbert, Delaney R. Kirchmeier, Jenny Huo, Hans-Peter Kiem, Cameron J. Turtle, Roland B. Walter

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Stealth transgenes enable CAR-T cells to evade host immune responses av David Millar, Rebecca Larson, Marcela V Maus, Amanda A Bouffard, Matthew J Frigault, Stefanie R Bailey, Mark B Leick, Michael C Kann, Cameron J Turtle, Trisha Berger, Kathleen Gallagher, Korneel Grauwet, Harrison Silva

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Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques av Nicholas E. Petty, Stefan Radtke, Greta Kanestrom, Emily Fields, Olivier Humbert, Salvatore Fiorenza, Mallory J. Llewellyn, George S. Laszlo, Justin Thomas, Zach Burger, Kyle Swing, Haiying Zhu, Keith R. Jerome, Cameron J. Turtle, Roland B. Walter, Hans-Peter Kiem

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Durable preservation of antiviral antibodies after CD19-directed chimeric antigen receptor T-cell immunotherapy av Joshua A. Hill, Elizabeth M. Krantz, Kevin A. Hay, Sayan Dasgupta, Terry Stevens-Ayers, Rachel A. Bender Ignacio, Merav Bar, Joyce Maalouf, Sindhu Cherian, Xueyan Chen, Greg Pepper, Stanley R. Riddell, David G. Maloney, Michael J. Boeckh, Cameron J. Turtle

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A novel dose-dense strategy for CD19-directed CAR T-cell therapy is associated with durable responses without increased toxicity in patients with B-cell non-Hodgkin lymphoma av Valentín Ortiz-Maldonado, Emily C. Liang, Jennifer J. Huang, Yein Jeon, Alexandre V. Hirayama, Erik L. Kimble, Andrew J. Portuguese, Christy Khouderchah, Kristina Braathen, Aiko Torkelson, Delaney Kirchmeier, Mazyar Shadman, David G. Maloney, Stanley R. Riddell, Cameron J. Turtle, Jordan Gauthier

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Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy av Mazyar Shadman, Jordan Gauthier, Kevin A. Hay, Jenna M. Voutsinas, Filippo Milano, Ang Li, Alexandre V. Hirayama, Mohamed L. Sorror, Sindhu Cherian, Xueyan Chen, Ryan D. Cassaday, Brian G. Till, Ajay K. Gopal, Brenda M. Sandmaier, David G. Maloney, Cameron J. Turtle

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Novel antibodies for identification, selection, and manipulation of T cells expressing Whitlow linker-containing CARs av Alexandre Hirayama, Cecilia CS Yeung, Cameron J Turtle, Eric Tam, Kristen R Shimp, Brandon W Seaton, Jason P Price, David Jellyman, Jordan Gauthier, Erik L Kimble, Jocelyn H Wright, Aiko Torkelson, Kristina Braathen, Delaney R Kirchmeier, Raymond O Ruff, Orpheus Kolokythas, Norman E Boiani

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NKTR-255 enhances complete response following CD19 CAR T-cell therapy in patients with relapsed/refractory large B-cell lymphoma av Sairah Ahmed, John DiPersio, James Essell, Catherine Diefenbach, Miguel-Angel Perales, Cristina Castilla-Llorente, Saurabh Dahiya, Yi Liu, Heng Xu, Christie Fanton, Sohail Chaudhry, Zachary H. Lee, A. Mario Q. Marcondes, Mary A. Tagliaferri, Jonathan Zalevsky, David Miklos, Cameron J. Turtle, Joseph McGuirk

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Real-world outcomes with tisagenlecleucel in aggressive B-cell lymphoma: subgroup analyses from the CIBMTR registry av Frederick L Locke, Grant Schofield, Marcelo Pasquini, Matthew J Frigault, Cameron J Turtle, Stephen Lim, Brian Hill, Samantha Jaglowski, Caron A Jacobson, Gunjan Shah, Daniel J Landsburg, Michael Heim, Stephen Ronan Foley, Ron Ram, Peter A Riedell, Leslie L Popplewell, Ranjan Tiwari, Marta Majdan, Aisha Masood

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Influence of B cell-lineage targeted CAR-T cell therapy on humoral immunity and vaccine-induced antibody response av Stosh Ozog, Elizabeth M. Krantz, Karyn Tindbaek, Julian Munoz, Winnie L. Liu, Clementine Chalal, Sara Pernikoff, Khaleel Yahya, Terry Stevens-Ayers, Sayan Dasgupta, Andrew J. Cowan, Damian J. Green, Jordan Gauthier, Brian G. Till, Rebecca A. Gardner, Mazyar Shadman, Marie Bleakley, Michael Boeckh, Jim Boonyaratanakornkit, Cameron J. Turtle, Joshua A. Hill

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Phase 1 study of CD19 CAR T-cell therapy harboring a fully human scFv in CAR-naïve adult patients with B-ALL av Jordan Gauthier, Emily C. Liang, Jennifer J. Huang, Erik L. Kimble, Alexandre V. Hirayama, Salvatore Fiorenza, Jenna M. Voutsinas, Qian (Vicky) Wu, Carla A. Jaeger-Ruckstuhl, Barbara S. Pender, Delaney R. Kirchmeier, Aiko Torkelson, Kristina Braathen, Ryan Basom, Mazyar Shadman, Noam E. Kopmar, Ryan D. Cassaday, Stanley R. Riddell, David G. Maloney, Cameron J. Turtle

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Nivolumab following CAR-T failure in multiple myeloma and non-Hodgkin lymphoma: results of a phase 2 study av Rahul Banerjee, Sylvain Simon, Jenna M. Voutsinas, Qian Vicky Wu, Daria Gausman, Joshua Dizon, Ethan Xie, Cecilia C. S. Yeung, Minggang Lin, Ryan C. Lynch, Chaitra S. Ujjani, Brian G. Till, Mary L. Kwok, Sarah S. Lee, Rebecca Silbermann, Eva Medvedova, Peter Wilcox, Jorge Ramos, Mazyar Shadman, Jordan Gauthier, Cameron J. Turtle, Damian J. Green, Ajay K. Gopal, Stanley R. Riddell, Andrew J. Cowan

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events av Frederick L Locke, Stephan A Grupp, Elizabeth J Shpall, Sattva S Neelapu, Michael R Bishop, Marcela V Maus, Jorg Dietrich, Daniel W Lee, Matthew J Frigault, Terry J Fry, Sara Alexander, Jennifer N Brudno, Colleen Callahan, Marco L Davila, Claudia Diamonte, Julie C Fitzgerald, Jennifer L Holter-Chakrabarty, Krishna V Komanduri, Shannon L Maude, Philip L McCarthy, Elena Mead, Tomas G Neilan, Bianca D Santomasso, David T Teachey, Cameron J Turtle, Tom Whitehead

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Development and validation of predictive models of early immune effector cell–associated hematotoxicity av Emily C. Liang, Jennifer J. Huang, Andrew J. Portuguese, Valentín Ortiz-Maldonado, Aya Albittar, Natalie Wuliji, Ryan Basom, Yein Jeon, Qian Wu, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mohamed Sorror, Joshua A. Hill, Noam E. Kopmar, Rahul Banerjee, Andrew J. Cowan, Damian Green, Ajay K. Gopal, Christina Poh, Mazyar Shadman, Alexandre V. Hirayama, Brian G. Till, Erik L. Kimble, Lorenzo Iovino, Aude G. Chapuis, Folashade Otegbeye, Ryan D. Cassaday, Filippo Milano, Cameron J. Turtle, David G. Maloney, Jordan Gauthier

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Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity av Aaron Bodansky, David J.L. Yu, Alysa Rallistan, Muge Kalaycioglu, Jim Boonyaratanakornkit, Damian J. Green, Jordan Gauthier, Cameron J. Turtle, Kelsey Zorn, Brian O’Donovan, Caleigh Mandel-Brehm, James Asaki, Hannah Kortbawi, Andrew F. Kung, Elze Rackaityte, Chung-Yu Wang, Aditi Saxena, Kimberly de Dios, Gianvito Masi, Richard J. Nowak, Kevin C. O’Connor, Hao Li, Valentina E. Diaz, Rowan Saloner, Kaitlin B. Casaletto, Eva Q. Gontrum, Brandon Chan, Joel H. Kramer, Michael R. Wilson, Paul J. Utz, Joshua A. Hill, Shaun W. Jackson, Mark S. Anderson, Joseph L. DeRisi

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New comorbidity index associated with survival after chimeric antigen receptor T-cell therapy for large B-cell lymphoma av Uri Greenbaum, Hamza Hashmi, Mahmoud Elsawy, Soyoung Kim, Amy Moskop, Temitope Oloyede, Farrukh T. Awan, Veronika Bachanova, Talha Badar, Merav Bar, Pere Barba, Amer M. Beitinjaneh, Amanda Cashen, Bhagirathbhai Dholaria, Umar Farooq, Jessica Foglesong, Siddhartha Ganguly, Peiman Hematti, LaQuisa C. Hill, Michael D. Jain, Tania Jain, Partow Kebriaei, Adam S. Kittai, Frederick L. Locke, Premal D. Lulla, Joseph P. McGuirk, Elena Mead, Alberto Mussetti, Taiga Nishihori, Amanda L. Olson, Martina Pennisi, Miguel-Angel Perales, Praveen Ramakrishnan Geethakumari, Peter A. Riedell, Wael Saber, Roni Shouval, Elizabeth J. Shpall, Margarida Magalhaes-Silverman, Christopher Strouse, Cameron J. Turtle, Anusha Vallurupalli, Kitsada Wudhikarn, Marcelo C. Pasquini, Sairah Ahmed, Mohamed Sorror

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