نتائج البحث - Bryan L. Roth

Nanobody-drug conjugates for targeting specific GPCR pairs. حسب Xianglin Huang, Bryan L Roth

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The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice حسب Vladimir M. Pogorelov, Ramona M. Rodriguiz, Ramona M. Rodriguiz, Bryan L. Roth, Bryan L. Roth, William C. Wetsel, William C. Wetsel, William C. Wetsel

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Agonist and antagonist TRUPATH assays for G protein-coupled receptors حسب Jeffrey F. DiBerto, Katie Smart, Reid H.J. Olsen, Bryan L. Roth

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The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor. حسب Bryan L Roth, Simon Gibbons, Warunya Arunotayanun, Xi-Ping Huang, Vincent Setola, Ric Treble, Les Iversen

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Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor. حسب Bryan L Roth, Simon Gibbons, Warunya Arunotayanun, Xi-Ping Huang, Vincent Setola, Ric Treble, Les Iversen

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trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT2 receptor family حسب Adam Pigott, Stewart Frescas, John D. McCorvy, Xi-Ping Huang, Bryan L. Roth, David E. Nichols

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Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D1 Receptor حسب David Y. W. Lee, Lee-Yuan Liu-Chen, Bryan L. Roth, Niels H. Jensen, Wei Xu, Zhong-Ze Ma

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LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1 حسب Ramona M. Rodriguiz, Vineet Nadkarni, Christopher R. Means, Vladimir M. Pogorelov, Yi-Ting Chiu, Bryan L. Roth, William C. Wetsel

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A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. حسب John D Chan, John D McCorvy, Sreemoyee Acharya, Malcolm E Johns, Timothy A Day, Bryan L Roth, Jonathan S Marchant

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Securinine, a myeloid differentiation agent with therapeutic potential for AML. حسب Kalpana Gupta, Amitabha Chakrabarti, Sonia Rana, Ritu Ramdeo, Bryan L Roth, Munna L Agarwal, William Tse, Mukesh K Agarwal, David N Wald

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DREADDs in Drosophila: A Pharmacogenetic Approach for Controlling Behavior, Neuronal Signaling, and Physiology in the Fly حسب Jaime Becnel, Oralee Johnson, Zana R. Majeed, Vi Tran, Bangning Yu, Bryan L. Roth, Robin L. Cooper, Edmund K. Kerut, Charles D. Nichols

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Far away from the lamppost. حسب Tudor I Oprea, Lily Jan, Gary L Johnson, Bryan L Roth, Avi Ma'ayan, Stephan Schürer, Brian K Shoichet, Larry A Sklar, Michael T McManus

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Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome حسب Michael V. Morabito, Atheir I. Abbas, Jennifer L. Hood, Robert A. Kesterson, Michelle M. Jacobs, David S. Kump, David L. Hachey, Bryan L. Roth, Ronald B. Emeson

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In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. حسب George A Lemieux, Michael J Keiser, Maria F Sassano, Christian Laggner, Fahima Mayer, Roland J Bainton, Zena Werb, Bryan L Roth, Brian K Shoichet, Kaveh Ashrafi

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Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. حسب Thomas A Munro, Xi-Ping Huang, Carmela Inglese, Maria Grazia Perrone, Ashlee Van't Veer, F Ivy Carroll, Cécile Béguin, William A Carlezon, Nicola A Colabufo, Bruce M Cohen, Bryan L Roth

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The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand حسب John D. Chan, Pauline M. Cupit, Gihan S. Gunaratne, John D. McCorvy, Yang Yang, Kristen Stoltz, Thomas R. Webb, Peter I. Dosa, Bryan L. Roth, Ruben Abagyan, Charles Cunningham, Jonathan S. Marchant

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Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation حسب Gavin P. Schmitz, Yi-Ting Chiu, Mia L. Foglesong, Sarah N. Magee, Martin MacKinnon, Gabriele M. König, Evi Kostenis, Li-Ming Hsu, Yen-Yu I. Shih, Bryan L. Roth, Melissa A. Herman

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Nanobody-enabled monitoring of kappa opioid receptor states حسب Tao Che, Justin English, Brian E. Krumm, Kuglae Kim, Els Pardon, Reid H. J. Olsen, Sheng Wang, Shicheng Zhang, Jeffrey F. Diberto, Noah Sciaky, F. Ivy Carroll, Jan Steyaert, Daniel Wacker, Bryan L. Roth

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Structural characterization of kappa-opioid receptor dimer in complex with two G proteins حسب Yuxi Zhao, Chanjuan Xu, Yue Wang, Hong Shan, Jing Wang, Yuxuan Liu, Xin Luo, Junrui Li, Mingyang Li, Yini Liu, Kai Wu, Bryan L. Roth, Xi-Ping Huang, H. Eric Xu, Jianfeng Liu, Youwen Zhuang

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A proximity proteomics pipeline with improved reproducibility and throughput حسب Xiaofang Zhong, Qiongyu Li, Benjamin J Polacco, Trupti Patil, Aaron Marley, Helene Foussard, Prachi Khare, Rasika Vartak, Jiewei Xu, Jeffrey F DiBerto, Bryan L Roth, Manon Eckhardt, Mark von Zastrow, Nevan J Krogan, Ruth Hüttenhain

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