Reactivity of 3-Ethoxycarbonyl Isoquinolinium Salts Towards Various Nucleophilic Reagents: Applications to the Synthesis of New 1,2-Dihydroisoquinoline-3-carboxylates

por Meziane, Mohamed Ameziane Aït Amer, Bazureau, Jean Pierre
Publicado en Molecules (2002)

Reactivity of 2-Thiohydantoins Towards Various Electrophilic Reagents: Applications to the Synthesis of New 2-Ylidene-3,5-dihydro-4H-imidazol-4-ones

por Chérouvrier, Jean-René, Carreaux, François, Bazureau, Jean Pierre
Publicado en Molecules (2004)

A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene-1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

por Bourahla, Khadidja, Paquin, Ludovic, Lozach, Olivier, Meijer, Laurent, Carreaux, François, Bazureau, Jean Pierre
Publicado en Molecules (2011)

Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors

por Dago, Camille D., Maux, Paul Le, Roisnel, Thierry, Brigaudeau, Christophe, Bekro, Yves-Alain, Mignen, Olivier, Bazureau, Jean-Pierre
Publicado en Int J Mol Sci (2018)

Microwave-Assisted Condensation Reactions of Acetophenone Derivatives and Activated Methylene Compounds with Aldehydes Catalyzed by Boric Acid under Solvent-Free Conditions

por Brun, Elodie, Safer, Abdelmounaim, Carreaux, François, Bourahla, Khadidja, L’helgoua’ch, Jean-Martial, Bazureau, Jean-Pierre, Villalgordo, Jose Manuel
Publicado en Molecules (2015)

cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease

por Fant, Xavier, Durieu, Emilie, Chicanne, Gaëtan, Payrastre, Bernard, Sbrissa, Diego, Shisheva, Assia, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Meijer, Laurent
Publicado en Mol Pharmacol (2014)

Synthesis of New N,N’-Bis(5-arylidene-4-oxo-4,5-dihydrothiazolin-2-yl)piperazine Derivatives Under Microwave Irradiation and Preliminary Biological Evaluation

por Coulibaly, Wacothon Karime, Paquin, Ludovic, Bénié, Anoubilé, Bekro, Yves-Alain, Durieux, Emilie, Meijer, Laurent, Le Guével, Rémy, Corlu, Anne, Bazureau, Jean-Pierre
Publicado 2012

Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

por Dago, Camille Déliko, Ambeu, Christelle N´ta, Coulibaly, Wacothon-Karime, Békro, Yves-Alain, Mamyrbékova, Janat, Defontaine, Audrey, Baratte, Blandine, Bach, Stéphane, Ruchaud, Sandrine, Le Guével, Rémy, Ravache, Myriam, Corlu, Anne, Bazureau, Jean-Pierre
Publicado en Molecules (2015)

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

por Nguyen, Thu Lan, Duchon, Arnaud, Manousopoulou, Antigoni, Loaëc, Nadège, Villiers, Benoît, Pani, Guillaume, Karatas, Meltem, Mechling, Anna E., Harsan, Laura-Adela, Limanton, Emmanuelle, Bazureau, Jean-Pierre, Carreaux, François, Garbis, Spiros D., Meijer, Laurent, Herault, Yann
Publicado en Dis Model Mech (2018)

Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases

por Loaëc, Nadège, Attanasio, Eletta, Villiers, Benoît, Durieu, Emilie, Tahtouh, Tania, Cam, Morgane, Davis, Rohan A., Alencar, Aline, Roué, Mélanie, Bourguet-Kondracki, Marie-Lise, Proksch, Peter, Limanton, Emmanuelle, Guiheneuf, Solène, Carreaux, François, Bazureau, Jean-Pierre, Klautau, Michelle, Meijer, Laurent
Publicado en Mar Drugs (2017)

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

por Souchet, Benoît, Audrain, Mickael, Billard, Jean Marie, Dairou, Julien, Fol, Romain, Orefice, Nicola Salvatore, Tada, Satoru, Gu, Yuchen, Dufayet-Chaffaud, Gaelle, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Alves, Sandro, Meijer, Laurent, Janel, Nathalie, Braudeau, Jérôme, Cartier, Nathalie
Publicado en Acta Neuropathol Commun (2019)