Risultati della ricerca - BIOS Consortium

Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs di Jenny van Dongen, Gonneke Willemsen, BIOS Consortium, Eco JC de Geus, Dorret I Boomsma, Michael C Neale

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Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits di Eleonora Porcu, Sina Rüeger, Kaido Lepik, eQTLGen Consortium, BIOS Consortium, Federico A. Santoni, Alexandre Reymond, Zoltán Kutalik

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Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids di Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, BIOS Consortium, Harm-Jan Westra, Yang Li, Cisca Wijmenga, Serena Sanna

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The inactive X chromosome accumulates widespread epigenetic variability with age di Yunfeng Liu, Lucy Sinke, Thomas H. Jonkman, Roderick C. Slieker, BIOS Consortium, Erik W. van Zwet, Lucia Daxinger, Bastiaan T. Heijmans

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Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data di Arno van Hilten, Jeroen van Rooij, BIOS consortium, M. Arfan Ikram, Wiro J. Niessen, Joyce. B. J. van Meurs, Gennady V. Roshchupkin

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Correction for both common and rare cell types in blood is important to identify genes that correlate with age di Damiano Pellegrino-Coppola, Annique Claringbould, Maartje Stutvoet, BIOS Consortium, Dorret I. Boomsma, M. Arfan Ikram, P. Eline Slagboom, Harm-Jan Westra, Lude Franke

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PICALO: principal interaction component analysis for the identification of discrete technical, cell-type, and environmental factors that mediate eQTLs di Martijn Vochteloo, Patrick Deelen, Britt Vink, BIOS Consortium, Ellen A. Tsai, Heiko Runz, Sergio Andreu-Sánchez, Jingyuan Fu, Alexandra Zhernakova, Harm-Jan Westra, Lude Franke

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Limited evidence for blood eQTLs in human sexual dimorphism di Eleonora Porcu, Annique Claringbould, Antoine Weihs, Kaido Lepik, BIOS Consortium, Tom G. Richardson, Uwe Völker, Federico A. Santoni, Alexander Teumer, Lude Franke, Alexandre Reymond, Zoltán Kutalik

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Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults di Mi Kyeong Lee, Cheng-Jian Xu, Megan U. Carnes, Cody E. Nichols, James M. Ward, The BIOS consortium, Sung Ok Kwon, Sun-Young Kim, Woo Jin Kim, Stephanie J. London

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Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies di Anna Niehues, Daniele Bizzarri, Marcel J.T. Reinders, P. Eline Slagboom, Alain J. van Gool, Erik B. van den Akker, BBMRI-NL BIOS consortium, BBMRI-NL Metabolomics consortium, Peter A.C. ’t Hoen

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Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies di Jeroen van Rooij, Pooja R. Mandaviya, Annique Claringbould, Janine F. Felix, Jenny van Dongen, Rick Jansen, Lude Franke, BIOS consortium, Peter A. C. ’t Hoen, Bas Heijmans, Joyce B. J. van Meurs

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DNA methylation is associated with lung function in never smokers di Maaike de Vries, Ivana Nedeljkovic, Diana A. van der Plaat, Alexandra Zhernakova, Lies Lahousse, Guy G. Brusselle, BIOS Consortium, Najaf Amin, Cornelia M. van Duijn, Judith M. Vonk, H. Marike Boezen

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Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure di Roy Oelen, Dylan H. de Vries, Harm Brugge, M. Grace Gordon, Martijn Vochteloo, single-cell eQTLGen consortium, BIOS Consortium, Chun J. Ye, Harm-Jan Westra, Lude Franke, Monique G. P. van der Wijst

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Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response di Koen F. Dekkers, Roderick C. Slieker, Andreea Ioan-Facsinay, Maarten van Iterson, BIOS consortium, M. Arfan Ikram, Marleen M. J. van Greevenbroek, Jan H. Veldink, Lude Franke, Dorret I. Boomsma, P. Eline Slagboom, J. Wouter Jukema, Bastiaan T. Heijmans

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Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification di Xiaoling Zhang, Jeroen G. J. van Rooij, Yoshiyuki Wakabayashi, Shih-Jen Hwang, Yanqin Yang, Mohsen Ghanbari, Daniel Bos, BIOS Consortium, Daniel Levy, Andrew D. Johnson, Joyce B. J. van Meurs, Maryam Kavousi, Jun Zhu, Christopher J. O’Donnell

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A SNP panel for identification of DNA and RNA specimens di Soheil Yousefi, Tooba Abbassi-Daloii, Thirsa Kraaijenbrink, Martijn Vermaat, Hailiang Mei, Peter van ‘t Hof, Maarten van Iterson, Daria V. Zhernakova, Annique Claringbould, Lude Franke, Leen M. ‘t Hart, Roderick C. Slieker, Amber van der Heijden, Peter de Knijff, BIOS consortium, Peter A. C. ’t Hoen

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RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting di Bharati Jadhav, Ramin Monajemi, Kristina K. Gagalova, Daniel Ho, Harmen H. M. Draisma, Mark A. van de Wiel, Lude Franke, Bastiaan T. Heijmans, Joyce van Meurs, Rick Jansen, GoNL Consortium, BIOS Consortium, Peter A. C. ‘t Hoen, Andrew J. Sharp, Szymon M. Kiełbasa

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Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data di Shuang Li, Katharina T. Schmid, Dylan H. de Vries, Maryna Korshevniuk, Corinna Losert, Roy Oelen, Irene V. van Blokland, BIOS Consortium, sc-eQTLgen Consortium, Hilde E. Groot, Morris A. Swertz, Pim van der Harst, Harm-Jan Westra, Monique G.P. van der Wijst, Matthias Heinig, Lude Franke

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Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins di Gabin Drouard, Fiona A. Hagenbeek, Alyce M. Whipp, René Pool, Jouke Jan Hottenga, Rick Jansen, Nikki Hubers, Aleksei Afonin, BIOS Consortium, BBMRI-N. L. Metabolomics Consortium, Gonneke Willemsen, Eco J. C. de Geus, Samuli Ripatti, Matti Pirinen, Katja M. Kanninen, Dorret I. Boomsma, Jenny van Dongen, Jaakko Kaprio

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Genetic and environmental influences interact with age and sex in shaping the human methylome di Jenny van Dongen, Michel G. Nivard, Gonneke Willemsen, Jouke-Jan Hottenga, Quinta Helmer, Conor V. Dolan, Erik A. Ehli, Gareth E. Davies, Maarten van Iterson, Charles E. Breeze, Stephan Beck, BIOS Consortium, H. Eka Suchiman, Rick Jansen, Joyce B. van Meurs, Bastiaan T. Heijmans, P. Eline Slagboom, Dorret I. Boomsma

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