Canlyniadau Chwilio - Anil K Rustgi

Cancer-Associated Fibroblasts in Esophageal CancerSummary gan Karen J. Dunbar, Kwok K. Wong, Anil K. Rustgi

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When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex gan Chenchen Li, Emma E. Furth, Anil K. Rustgi, Peter S. Klein

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TransST: transfer learning embedded spatial factor modeling of spatial transcriptomics data gan Shuo Shuo Liu, Shikun Wang, Yuxuan Chen, Anil K. Rustgi, Ming Yuan, Jianhua Hu

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Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53 gan Rafaela Muniz de Queiroz, Gizem Efe, Asja Guzman, Naoko Hashimoto, Yusuke Kawashima, Tomoaki Tanaka, Anil K. Rustgi, Carol Prives

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Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia gan Peiman Habibollahi, Todd Waldron, Pedram Heidari, Hoon Sung Cho, David Alcantara, Lee Josephson, Timothy C. Wang, Anil K. Rustgi, Umar Mahmood

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Comparative transcriptomes of adenocarcinomas and squamous cell carcinomas reveal molecular similarities that span classical anatomic boundaries. gan Eric W Lin, Tatiana A Karakasheva, Dong-Jin Lee, Ju-Seog Lee, Qi Long, Adam J Bass, Kwok K Wong, Anil K Rustgi

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IL-1β transgenic mouse model of inflammation driven esophageal and oral squamous cell carcinoma gan Sureshkumar Muthupalani, Damodaran Annamalai, Yan Feng, Suresh M. Ganesan, Zhongming Ge, Mark T. Whary, Hiroshi Nakagawa, Anil K. Rustgi, Timothy C. Wang, James G. Fox

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LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3 gan Kensuke Sugiura, Yasunori Masuike, Kensuke Suzuki, Alice E. Shin, Nozomu Sakai, Hisahiro Matsubara, Masayuki Otsuka, Peter A. Sims, Christopher J. Lengner, Anil K. Rustgi

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Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets gan Ricardo Cruz-Acuña, Secunda W. Kariuki, Kensuke Sugiura, Spyros Karaiskos, Eleanor M. Plaster, Claudia Loebel, Gizem Efe, Tatiana Karakasheva, Joel T. Gabre, Jianhua Hu, Jason A. Burdick, Anil K. Rustgi

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High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer gan Natalie Thielen, Ning Wei, Emiko Nagai, Michele Houston, Leonard H. Augenlicht, Alice E. Shin, Joel T. Gabre, Anil K. Rustgi, Grace Ha, Lindsay M. LaFave, Edward Chu, Seiya Kitamura, Chaoyuan Kuang

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LIN28B-mediated PI3K/AKT pathway activation promotes metastasis in colorectal cancer models gan Alice E. Shin, Kensuke Sugiura, Secunda W. Kariuki, David A. Cohen, Samuel P. Flashner, Andres J. Klein-Szanto, Noriyuki Nishiwaki, Dechokyab De, Neil Vasan, Joel T. Gabre, Christopher J. Lengner, Peter A. Sims, Anil K. Rustgi

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Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity gan Jillian S. Weissenrieder, Jessica Peura, Usha Paudel, Nikita Bhalerao, Natalie Weinmann, Calvin Johnson, Maximilian Wengyn, Rebecca Drager, Emma Elizabeth Furth, Karl Simin, Marcus Ruscetti, Ben Z. Stanger, Anil K. Rustgi, Jason R. Pitarresi, J. Kevin Foskett

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A generalizable cross-continent prediction of esophageal squamous cell carcinoma using the oral microbiome gan Shahd ElNaggar, Wenlong Carl Chen, Leanne M. Prodehl, Thomas K. Marumo, Muhammed U. Khan, Christopher G. Mathew, Paul Ruff, Zhezhen Jin, Alfred I. Neugut, Anil K. Rustgi, Anne-Catrin Uhlemann, Tal Korem, Julian A. Abrams

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Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer gan Kyung-Pil Ko, Shengzhe Zhang, Yuanjian Huang, Bongjun Kim, Gengyi Zou, Sohee Jun, Jie Zhang, Yahui Zhao, Cecilia Martin, Karen J. Dunbar, Gizem Efe, Anil K. Rustgi, Hiroshi Nakagawa, Haiyang Zhang, Zhihua Liu, Jae-Il Park

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Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. gan Marina Pasca di Magliano, Andrew V Biankin, Patrick W Heiser, David A Cano, Pedro J A Gutierrez, Therese Deramaudt, Davendra Segara, Amanda C Dawson, James G Kench, Susan M Henshall, Robert L Sutherland, Andrzej Dlugosz, Anil K Rustgi, Matthias Hebrok

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A Cell Marker Atlas to Distinguish Metaplastic Transitions in Human Esophagus and Stomach gan Karen J. Dunbar, Su-Hyung Lee, Yoonkyung Won, Emily M. Esquea, Jeong Yun Yang, Daniel O. Kechele, Sandra Ryeom, Julian A. Abrams, Frank D. McKeon, James M. Wells, Micheal Quante, Eunyoung Choi, Jianwen Que, Timothy C. Wang, Anil K. Rustgi, James R. Goldenring

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Increased reflux secondary bile acids are associated with changes to the microbiome and transcriptome in Barrett’s esophagus gan Ceylan Tanes, Yun Li, Gary W. Falk, Gregory G. Ginsberg, Kenneth K. Wang, Prasad G. Iyer, Charles J. Lightdale, Armando Del Portillo, Stephen M. Lagana, Timothy C. Wang, Anil K. Rustgi, Michael Quante, Zhezhen Jin, Gary D. Wu, Elliot S. Friedman, Kyle Bittinger, Hongzhe Li, Julian A. Abrams

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Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury gan Sabyasachi Bhattacharya, Kanstantsin V Katlinski, Maximilian Reichert, Shigetsugu Takano, Angela Brice, Bin Zhao, Qiujing Yu, Hui Zheng, Christopher J Carbone, Yuliya V Katlinskaya, N Adrian Leu, Kelly A McCorkell, Satish Srinivasan, Melanie Girondo, Hallgeir Rui, Michael J May, Narayan G Avadhani, Anil K Rustgi, Serge Y Fuchs

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411 Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis gan David Falvo, Adrien Grimont, David J Falvo, Whitney J Sisso, Paul Zumbo, Christopher W Chan, Francisco Santos, Grace Pan, Megan Cleveland, Tomer M Yaron, Alexa Osterhoudt, Yinuo Meng, Maria Paz Zafra, William B Fall, Andre F Rendeiro, Erika Hissong, Rhonda K Yantiss, Doron Betel, Mark A Magnuson, Steven D Leach, Anil K Rustgi, Lukas E Dow, Rohit Chandwani

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Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth gan Jason R Pitarresi, Xin Liu, Alex Avendano, Katie A Thies, Gina M Sizemore, Anisha M Hammer, Blake E Hildreth, David J Wang, Sarah A Steck, Sydney Donohue, Maria C Cuitiño, Raleigh D Kladney, Thomas A Mace, Jonathan J Chang, Christina S Ennis, Huiqing Li, Roger H Reeves, Seth Blackshaw, Jianying Zhang, Lianbo Yu, Soledad A Fernandez, Wendy L Frankel, Mark Bloomston, Thomas J Rosol, Gregory B Lesinski, Stephen F Konieczny, Denis C Guttridge, Anil K Rustgi, Gustavo Leone, Jonathan W Song, Jinghai Wu, Michael C Ostrowski

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