Resultados de procura - Alexander Muik

Clinical development of variant-adapted BNT162b2 COVID-19 vaccines: the early Omicron era por Shanti Pather, Alexander Muik, Ruben Rizzi, Federico Mensa

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Developing variant-adapted COVID-19 vaccines to improve protection against Omicron and other recent variants: a plain language summary por Shanti Pather, Alexander Muik, Ruben Rizzi, Federico Mensa

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Corrigendum: SARS-CoV-2 Omicron variants: burden of disease, impact on vaccine effectiveness and need for variant-adapted vaccines por Shanti Pather, Shabir A. Madhi, Benjamin J. Cowling, Paul Moss, Jeremy P. Kamil, Sandra Ciesek, Alexander Muik, Özlem Türeci

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Toxicological Assessments of a Pandemic COVID-19 Vaccine—Demonstrating the Suitability of a Platform Approach for mRNA Vaccines por Cynthia M. Rohde, Claudia Lindemann, Michael Giovanelli, Rani S. Sellers, Jan Diekmann, Shambhunath Choudhary, Lila Ramaiah, Annette B. Vogel, Yana Chervona, Alexander Muik, Ugur Sahin

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1181 GEN1042-mIgG2a, an Fc-inert mouse-human chimeric variant of GEN1042 (DuoBody®-CD40x4–1BB), exhibits in vivo antitumor activity and peripheral immune modulation por Karsten Pilones, Maria Jure-Kunkel, Homer Adams, Alexander Muik, Tahamtan Ahmadi, Ugur Sahin, Oezlem Tuereci, Kristina Nuermberger, Angelica Sette, Monique Luijten, Maren Köhne, Jasja Wolthoorn, Sina Fellermeier-Kopf

Immunity against conserved epitopes dominates after two consecutive exposures to SARS-CoV-2 Omicron BA.1 por Alexander Muik, Jasmin Quandt, Bonny Gaby Lui, Maren Bacher, Sebastian Lutz, Maika Grünenthal, Aras Toker, Jessica Grosser, Orkun Ozhelvaci, Olga Blokhina, Svetlana Shpyro, Isabel Vogler, Nadine Salisch, Özlem Türeci, Ugur Sahin

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Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA.1 infection por Chaitanya Kurhade, Jing Zou, Hongjie Xia, Mingru Liu, Qi Yang, Mark Cutler, David Cooper, Alexander Muik, Ugur Sahin, Kathrin U. Jansen, Ping Ren, Xuping Xie, Kena A. Swanson, Pei-Yong Shi

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813 Combination of HexaBody-CD27 with PD-(L)1 blockade potentiates single-agent activity leading to enhanced human T-cell effector functions in vitro por Jordan Blum, Alexander Muik, Isil Altintas, Friederike Gieseke, Aras Toker, Esther Breij, Tahamtan Ahmadi, Ugur Sahin, Kristel Kemper, Oezlem Tuereci, Kristina Nuermberger, Sina Fellermeier-Kopf, Andrea Imle, Anna-Lena Krause, Lidia Daszkiewicz

BNT162b2-elicited neutralization of Delta plus, Lambda, Mu, B.1.1.519, and Theta SARS-CoV-2 variants por Jianying Liu, Yang Liu, Hongjie Xia, Jing Zou, Scott C. Weaver, Kena A. Swanson, Hui Cai, Mark Cutler, David Cooper, Alexander Muik, Kathrin U. Jansen, Ugur Sahin, Xuping Xie, Philip R. Dormitzer, Pei-Yong Shi

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Strong and early immune responses against SARS-CoV-2 in mice and rhesus macaques after BNT162b3 vaccination por Annette B. Vogel, Bonny G. Lui, Kristin Tompkins, Isis Kanevsky, Alexander Muik, Stefanie A. Krumm, Alptekin Güler, Mohan S. Maddur, Kerstin C. Walzer, Sonja Witzel, Fulvia Vascotto, Eliana Stanganello, Ayuko Ota-Setlik, Kimberly J. Cottingham, Omaira Allbritton, Jessica Keverne, Letícia Aragão-Santiago, Kena A. Swanson, Özlem Türeci, Uğur Şahin

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A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade por Işıl Altıntaş, Kristina B. Nürmberger, Andrea Imle, Anna-Lena Krause, Marike M. van Beuge, Aras Toker, Andreea Ioan-Facsinay, Jordan Blum, Alexander Muik, Frank J. Beurskens, Rob N. de Jong, David P. E. Satijn, Friederike Gieseke, Bart-Jan de Kreuk, Maarten van der Kroef, Sina Fellermeier-Kopf, Tahamtan Ahmadi, Özlem Türeci, Esther C. W. Breij, Uğur Şahin

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Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects por Maria Jure-Kunkel, Christina Yu, Nora Pencheva, Mark Fereshteh, Alexander Muik, Aras Toker, Özlem Türeci, Tahamtan Ahmadi, Ugur Sahin, Brandon W Higgs, Jordan M Blum, Saskia M Burm, Vanessa M Spires, Angelica Sette, Sina Fellermeier-Kopf, Andrea Imle, Michela Capello, Kristin Strumane, Theo Plantinga, Craig J Thalhauser, Kristina B Nürmberger, Patricia Garrido Castro, Carol Costa Sa, Bruna de Andrade Pereira

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Immunologic and biophysical features of the BNT162b2 JN.1 and KP.2 adapted COVID-19 vaccines por Wei Chen, Kristin R. Tompkins, Ian W. Windsor, Lyndsey T. Martinez, Minah Ramos, Weiqiang Li, Shikha Shrivastava, Swati Rajput, Jeanne S. Chang, Parag Sahasrabudhe, Kimberly F. Fennell, Thomas J. McLellan, Graham M. West, Kristianne P. Dizon, Aaron Yam, Siddartha Mitra, Subrata Saha, Daiana Sharaf, Andrew P. McKeen, Carla I. Cadima, Alexander Muik, Wesley Swanson, Raquel Munoz Moreno, Pilar Mendoza Daroca, Ugur Sahin, Annaliesa S. Anderson, Huixian Wu, Kena A. Swanson, Kayvon Modjarrad

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Preclinical characterization of the Omicron XBB.1.5-adapted BNT162b2 COVID-19 vaccine por Kayvon Modjarrad, Ye Che, Wei Chen, Huixian Wu, Carla I. Cadima, Alexander Muik, Mohan S. Maddur, Kristin R. Tompkins, Lyndsey T. Martinez, Hui Cai, Minah Ramos, Sonia Mensah, Brittney Cumbia, Larissa Falcao, Andrew P. McKeen, Jeanne S. Chang, Kimberly F. Fennell, Kevin W. Huynh, Thomas J. McLellan, Parag V. Sahasrabudhe, Wei Chen, Michael Cerswell, Miguel A. Garcia, Shilong Li, Rahul Sharma, Weiqiang Li, Kristianne P. Dizon, Stacy Duarte, Frank Gillett, Rachel Smith, Deanne M. Illenberger, Kari Sweeney Efferen, Annette B. Vogel, Annaliesa S. Anderson, Uğur Şahin, Kena A. Swanson

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