Suchergebnisse - Alan Talevi

Clustering of small molecules: new perspectives and their impact on natural product lead discovery von Alan Talevi, Alan Talevi, Carolina L. Bellera, Carolina L. Bellera

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Application of machine learning to predict unbound drug bioavailability in the brain von J. Francisco Morales, J. Francisco Morales, M. Esperanza Ruiz, M. Esperanza Ruiz, Robert E. Stratford, Alan Talevi, Alan Talevi

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Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing von Carolina L. Bellera, Darío E. Balcazar, Lucas Alberca, Carlos A. Labriola, Alan Talevi, Carolina Carrillo

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Cannabidiol combined with GABAergic drugs but not with sodium channel blockers prevents the development of drug-resistance seizures in a preclinical model von Monserrat Fuentes-Mejia, Maximiliano J. Fallico, Alan Talevi, Luciana Gavernet, Sandra A. Orozco-Suárez, Luisa Rocha

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LIDEB's Useful Decoys (LUDe): A freely available decoy-generation tool. Benchmarking and scope von Lucas N. Alberca, Denis N. Prada Gori, Maximiliano J. Fallico, Alexandre V. Fassio, Alan Talevi, Carolina L. Bellera

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Crystal Structure of Melphalan Hydrochloride and Its Association with Caffeine Improves Its Antineoplastic Action von Juliana Pereira da Silva, Carin Cristina da Silva Batista, Maria Lúcia Schumacher, Santiago Rodriguez, Alan Talevi, Paula Haddad, Guillermo Raul Castro, Fabio Furlan Ferreira

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In Silico Screening Identification of Fatty Acids and Fatty Acid Derivatives with Antiseizure Activity: In Vitro and In Vivo Validation von Emilia Mercedes Barrionuevo, Estefanía Peralta, Agustín Manzur De Nardi, Juliana Monat, Maximiliano José Fallico, Manuel Augusto Llanos, Luciana Gavernet, Emilio Román Mustafá, Pedro Martin, Alan Talevi

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Lipid Nanoparticles with Stiripentol and Cannabidiol Oil: From Rational Optimization to Preclinical Characterization von Sebastián Scioli-Montoto, Martin Lobos, Mauricio Melis, Santiago Ruatta, Giuliana Muraca, Cecilia Yamil Chain, Sebastián Cisneros, Vera Alejandra Alvarez, German Islan, Alan Talevi, María Esperanza Ruiz

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Application of Data-Centric Supervised Machine Learning to Predict Phenotypic Activity Against Clinically Relevant Stages of <i>Trypanosoma cruzi</i> von Nicolás Pérez-Mauad, Lucas N. Alberca, Alejandra C. Schoijet, Salome C. Vilchez Larrea, Emilia M. Barrionuevo, Giuliana Muraca, Valeria Sülsen, Catalina D. Alba-Soto, Guillermo D. Alonso, Alan Talevi

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Advancing Trypanosoma cruzi N-myristoyltransferase as a drug target for Chagas disease through in silico discovery and biochemical evaluation von Diana González García, Angel Torres, Alan Talevi, Lucas N. Alberca, Miguel A. Beltran, Frida Lara, Marina Da Silva Ferreira, Marina Da Silva Ferreira, Priscila S. G. Farani, Priscila S. G. Farani, Igor C. Almeida, Rosa A. Maldonado

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Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease von Denis N. Prada Gori, Santiago Ruatta, Santiago Ruatta, Martín Fló, Martín Fló, Lucas N. Alberca, Carolina L. Bellera, Soonju Park, Jinyeong Heo, Honggun Lee, Kyu-Ho Paul Park, Otto Pritsch, Otto Pritsch, David Shum, Marcelo A. Comini, Alan Talevi

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Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies von Giuliana Muraca, María Esperanza Ruiz, Rocío C. Gambaro, Sebastián Scioli-Montoto, María Laura Sbaraglini, Gisel Padula, José Sebastián Cisneros, Cecilia Yamil Chain, Vera A. Álvarez, Cristián Huck-Iriart, Guillermo R. Castro, María Belén Piñero, Matias Ildebrando Marchetto, Catalina Alba Soto, Germán A. Islan, Alan Talevi

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Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro von Santiago M. Ruatta, Santiago M. Ruatta, Denis N. Prada Gori, Martín Fló Díaz, Martín Fló Díaz, Franca Lorenzelli, Karen Perelmuter, Lucas N. Alberca, Lucas N. Alberca, Carolina L. Bellera, Carolina L. Bellera, Andrea Medeiros, Andrea Medeiros, Gloria V. López, Gloria V. López, Mariana Ingold, Williams Porcal, Williams Porcal, Estefanía Dibello, Irina Ihnatenko, Conrad Kunick, Marcelo Incerti, Martín Luzardo, Maximiliano Colobbio, Maximiliano Colobbio, Juan Carlos Ramos, Juan Carlos Ramos, Eduardo Manta, Eduardo Manta, Lucía Minini, María Laura Lavaggi, Paola Hernández, Jonas Šarlauskas, César Sebastian Huerta García, Rafael Castillo, Alicia Hernández-Campos, Giovanni Ribaudo, Giuseppe Zagotto, Renzo Carlucci, Noelia S. Medrán, Guillermo R. Labadie, Maitena Martinez-Amezaga, Carina M. L. Delpiccolo, Ernesto G. Mata, Laura Scarone, Laura Posada, Gloria Serra, Theodora Calogeropoulou, Kyriakos Prousis, Anastasia Detsi, Mauricio Cabrera, Guzmán Alvarez, Adrián Aicardo, Adrián Aicardo, Adrián Aicardo, Verena Araújo, Verena Araújo, Verena Araújo, Cecilia Chavarría, Cecilia Chavarría, Lucija Peterlin Mašič, Melisa E. Gantner, Melisa E. Gantner, Manuel A. Llanos, Manuel A. Llanos, Santiago Rodríguez, Luciana Gavernet, Luciana Gavernet, Soonju Park, Jinyeong Heo, Honggun Lee, Kyu-Ho Paul Park, Mariela Bollati-Fogolín, Otto Pritsch, Otto Pritsch, David Shum, Alan Talevi, Alan Talevi, Marcelo A. Comini

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