Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, phase 1/2 trial

by Sharma, Padmanee, Callahan, Margaret K, Bono, Petri, Kim, Joseph, Spiliopoulou, Pavlina, Calvo, Emiliano, Pillai, Rathi N, Ott, Patrick A, de Braud, Filippo, Morse, Michael, Le, Dung T, Jaeger, Dirk, Chan, Emily, Harbison, Chris, Lin, Chen-Sheng, Tschaika, Marina, Azrilevich, Alex, Rosenberg, Jonathan E
Published in Lancet Oncol (2016)

Pimasertib Versus Dacarbazine in Patients With Unresectable NRAS-Mutated Cutaneous Melanoma: Phase II, Randomized, Controlled Trial with Crossover

by Lebbé, Celeste, Dutriaux, Caroline, Lesimple, Thierry, Kruit, Willem, Kerger, Joseph, Thomas, Luc, Guillot, Bernard, de Braud, Filippo, Garbe, Claus, Grob, Jean-Jacques, Loquai, Carmen, Ferraresi, Virginia, Robert, Caroline, Vasey, Paul, Conry, Robert, Isaacs, Richard, Espinosa, Enrique, Schueler, Armin, Massimini, Giorgio, Dréno, Brigitte
Published in Cancers (Basel) (2020)

The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breas...

by Catania, Chiara, Maur, Michela, Berardi, Rossana, Rocca, Andrea, Giacomo, Anna Maria Di, Spitaleri, Gianluca, Masini, Cristina, Pierantoni, Chiara, González-Iglesias, Reinerio, Zigon, Giulia, Tasciotti, Annaelisa, Giovannoni, Leonardo, Lovato, Valeria, Elia, Giuliano, Menssen, Hans D, Neri, Dario, Cascinu, Stefano, Conte, Pier Franco, de Braud, Filippo
Published in Cell Adh Migr (2015)

Single-Agent Panitumumab in Frail Elderly Patients With Advanced RAS and BRAF Wild-Type Colorectal Cancer: Challenging Drug Label to Light Up New Hope

by Pietrantonio, Filippo, Cremolini, Chiara, Aprile, Giuseppe, Lonardi, Sara, Orlandi, Armando, Mennitto, Alessia, Berenato, Rosa, Antoniotti, Carlotta, Casagrande, Mariaelena, Marsico, Valentina, Marmorino, Federica, Cardellino, Giovanni Gerardo, Bergamo, Francesca, Tomasello, Gianluca, Formica, Vincenzo, Longarini, Raffaella, Giommoni, Elisa, Caporale, Marta, Di Bartolomeo, Maria, Loupakis, Fotios, de Braud, Filippo
Published in Oncologist (2015)

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

by Vergani, Elisabetta, Di Guardo, Lorenza, Dugo, Matteo, Rigoletto, Sara, Tragni, Gabrina, Ruggeri, Roberta, Perrone, Federica, Tamborini, Elena, Gloghini, Annunziata, Arienti, Flavio, Vergani, Barbara, Deho, Paola, De Cecco, Loris, Vallacchi, Viviana, Frati, Paola, Shahaj, Eriomina, Villa, Antonello, Santinami, Mario, De Braud, Filippo, Rivoltini, Licia, Rodolfo, Monica
Published in Oncotarget (2015)

Clinical Impact of Pancreatic Metastases from Renal Cell Carcinoma: A Multicenter Retrospective Analysis

by Grassi, Paolo, Doucet, Ludovic, Giglione, Palma, Grünwald, Viktor, Melichar, Bohuslav, Galli, Luca, De Giorgi, Ugo, Sabbatini, Roberto, Ortega, Cinzia, Santoni, Matteo, Bamias, Aristotelis, Verzoni, Elena, Derosa, Lisa, Studentova, Hana, Pacifici, Monica, Coppa, Jorgelina, Mazzaferro, Vincenzo, de Braud, Filippo, Porta, Camillo, Escudier, Bernard, Procopio, Giuseppe
Published in PLoS One (2016)

Oral Capecitabine-Vinorelbine Is Associated with Longer Overall Survival When Compared to Single-Agent Capecitabine in Patients with Hormone Receptor-Positive Advanced Breast Cance...

by Vernieri, Claudio, Prisciandaro, Michele, Nichetti, Federico, Lobefaro, Riccardo, Peverelli, Giorgia, Ligorio, Francesca, Zattarin, Emma, Cona, Maria Silvia, Sepe, Pierangela, Corti, Francesca, Manglaviti, Sara, Brambilla, Marta, Re, Barbara, Belfiore, Antonino, Pruneri, Giancarlo, Celio, Luigi, Mariani, Gabriella, Bianchi, Giulia Valeria, Rivoltini, Licia, Capri, Giuseppe, de Braud, Filippo
Published in Cancers (Basel) (2020)

A Phase 1 Study of mTORC1/2 Inhibitor BI 860585 as a Single Agent or with Exemestane or Paclitaxel in Patients with Advanced Solid Tumors

by de Braud, Filippo, Machiels, Jean-Pascal H., Boggiani, Daniela, Rottey, Sylvie W.H., Duca, Matteo, Laruelle, Marie, Salvagni, Stefania, Damian, Silvia, Lapeire, Lore D.F., Tiseo, Marcello, Dermine, Alexandre, Ould-Kaci, Mahmoud, Braunger, Juergen, Rascher, Juliane, Fischer, Daniela, Hoefler, Josef, Mariani, Gabriella L., Cresta, Sara
Published in Cancers (Basel) (2020)

Clinical Behavior and Treatment Response of Epstein‐Barr Virus‐Positive Metastatic Gastric Cancer: Implications for the Development of Future Trials

by Corallo, Salvatore, Fucà, Giovanni, Morano, Federica, Salati, Massimiliano, Spallanzani, Andrea, Gloghini, Annunziata, Volpi, Chiara Costanza, Trupia, Desirè Viola, Lobefaro, Riccardo, Guarini, Vincenzo, Milione, Massimo, Cattaneo, Laura, Antista, Maria, Prisciandaro, Michele, Raimondi, Alessandra, Sposito, Carlo, Mazzaferro, Vincenzo, de Braud, Filippo, Pietrantonio, Filippo, Di Bartolomeo, Maria
Published in Oncologist (2020)

SMO mutations confer poor prognosis in malignant pleural mesothelioma

by Signorelli, Diego, Proto, Claudia, Botta, Laura, Trama, Annalisa, Tiseo, Marcello, Pasello, Giulia, Lo Russo, Giuseppe, Fabbri, Alessandra, Imbimbo, Martina, Busico, Adele, Prelaj, Arsela, Ferrara, Roberto, Galli, Giulia, De Toma, Alessandro, Tamborini, Elena, Pastorino, Ugo, de Braud, Filippo, Gatta, Gemma, Garassino, Marina Chiara, Ganzinelli, Monica
Published in Transl Lung Cancer Res (2020)

FOLFOXIRI‐Bevacizumab or FOLFOX‐Panitumumab in Patients with Left‐Sided RAS/BRAF Wild‐Type Metastatic Colorectal Cancer: A Propensity Score‐Based Analysis

by Pietrantonio, Filippo, Fucà, Giovanni, Rossini, Daniele, Schmoll, Hans‐Joachim, Bendell, Johanna C., Morano, Federica, Antoniotti, Carlotta, Corallo, Salvatore, Borelli, Beatrice, Raimondi, Alessandra, Marmorino, Federica, Niger, Monica, Boccaccino, Alessandra, Masi, Gianluca, Lonardi, Sara, Boni, Luca, de Braud, Filippo, Di Bartolomeo, Maria, Falcone, Alfredo, Cremolini, Chiara
Published in Oncologist (2021)

Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups

by Simbolo, Michele, Fassan, Matteo, Ruzzenente, Andrea, Mafficini, Andrea, Wood, Laura D., Corbo, Vincenzo, Melisi, Davide, Malleo, Giuseppe, Vicentini, Caterina, Malpeli, Giorgio, Antonello, Davide, Sperandio, Nicola, Capelli, Paola, Tomezzoli, Anna, Iacono, Calogero, Lawlor, Rita T., Bassi, Claudio, Hruban, Ralph H., Guglielmi, Alfredo, Tortora, Giampaolo, de Braud, Filippo, Scarpa, Aldo
Published 2014

Differential histopathologic parameters in colorectal cancer liver metastases resected after triplets plus bevacizumab or cetuximab: a pooled analysis of five prospective trials

by Cremolini, Chiara, Milione, Massimo, Marmorino, Federica, Morano, Federica, Zucchelli, Gemma, Mennitto, Alessia, Prisciandaro, Michele, Lonardi, Sara, Pellegrinelli, Alessio, Rossini, Daniele, Bergamo, Francesca, Aprile, Giuseppe, Urbani, Lucio, Morelli, Luca, Schirripa, Marta, Cardellino, Giovanni Gerardo, Fassan, Matteo, Fontanini, Gabriella, de Braud, Filippo, Mazzaferro, Vincenzo, Falcone, Alfredo, Pietrantonio, Filippo
Published in Br J Cancer (2018)

Derazantinib (ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive intrahepatic cholangiocarcinoma

by Mazzaferro, Vincenzo, El-Rayes, Bassel F., Droz dit Busset, Michele, Cotsoglou, Christian, Harris, William P., Damjanov, Nevena, Masi, Gianluca, Rimassa, Lorenza, Personeni, Nicola, Braiteh, Fadi, Zagonel, Vittorina, Papadopoulos, Kyriakos P., Hall, Terence, Wang, Yunxia, Schwartz, Brian, Kazakin, Julia, Bhoori, Sherrie, de Braud, Filippo, Shaib, Walid L.
Published in Br J Cancer (2018)

Benefit from anti-EGFRs in RAS and BRAF wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study

by Cremolini, Chiara, Benelli, Matteo, Fontana, Elisa, Pagani, Filippo, Rossini, Daniele, Fucà, Giovanni, Busico, Adele, Conca, Elena, Di Donato, Samantha, Loupakis, Fotios, Schirripa, Marta, Lonardi, Sara, Borelli, Beatrice, Ongaro, Elena, Eason, Katherine, Morano, Federica, Casagrande, Mariaelena, Fassan, Matteo, Sadanandam, Anguraj, de Braud, Filippo, Falcone, Alfredo, Pietrantonio, Filippo
Published in ESMO Open (2019)

Neoadjuvant eribulin mesylate following anthracycline and taxane in triple negative breast cancer: Results from the HOPE study

by Di Cosimo, Serena, La Verde, Nicla, Moretti, Anna, Cazzaniga, Marina Elena, Generali, Daniele, Bianchi, Giulia Valeria, Mariani, Luigi, Torri, Valter, Crippa, Flavio, Paolini, Biagio, Scaperrotta, Gianfranco, De Santis, Maria Carmen, Di Nicola, Massimo, Apolone, Giovanni, Gulino, Alessandro, Tripodo, Claudio, Colombo, Mario Paolo, Folli, Secondo, de Braud, Filippo
Published in PLoS One (2019)

Validation of the Role of Thrombin Generation Potential by a Fully Automated System in the Identification of Breast Cancer Patients at High Risk of Disease Recurrence

by Gomez-Rosas, Patricia, Pesenti, Marina, Verzeroli, Cristina, Giaccherini, Cinzia, Russo, Laura, Sarmiento, Roberta, Masci, Giovanna, Celio, Luigi, Minelli, Mauro, Gamba, Sara, Tartari, Carmen Julia, Tondini, Carlo, Giuliani, Francesco, Petrelli, Fausto, D'Alessio, Andrea, Gasparini, Giampietro, Labianca, Roberto, Santoro, Armando, De Braud, Filippo, Marchetti, Marina, Falanga, Anna
Published in TH Open (2021)

Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer: Results from the Phase II BASALT-1 Study

by Vansteenkiste, Johan F., Canon, Jean-Luc, De Braud, Filippo, Grossi, Francesco, De Pas, Tommaso, Gray, Jhanelle E., Su, Wu-Chou, Felip, Enriqueta, Yoshioka, Hiroshige, Gridelli, Cesare, Dy, Grace K., Thongprasert, Sumitra, Reck, Martin, Aimone, Paola, Vidam, Gena Atalla, Roussou, Pantelia, Wang, Ying A., Tomaso, Emmanuelle Di, Soria, Jean-Charles
Published in J Thorac Oncol (2015)

Prognostic impact of ATM mutations in patients with metastatic colorectal cancer

by Randon, Giovanni, Fucà, Giovanni, Rossini, Daniele, Raimondi, Alessandra, Pagani, Filippo, Perrone, Federica, Tamborini, Elena, Busico, Adele, Peverelli, Giorgia, Morano, Federica, Niger, Monica, Antista, Maria, Corallo, Salvatore, Saggio, Serena, Borelli, Beatrice, Zucchelli, Gemma, Milione, Massimo, Pruneri, Giancarlo, Di Bartolomeo, Maria, Falcone, Alfredo, de Braud, Filippo, Cremolini, Chiara, Pietrantonio, Filippo
Published in Sci Rep (2019)

Thrombotic biomarkers for risk prediction of malignant disease recurrence in patients with early stage breast cancer

by Giaccherini, Cinzia, Marchetti, Marina, Masci, Giovanna, Verzeroli, Cristina, Russo, Laura, Celio, Luigi, Sarmiento, Roberta, Gamba, Sara, Tartari, Carmen J., Diani, Erika, Vignoli, Alfonso, Malighetti, Paolo, Spinelli, Daniele, Tondini, Carlo, Barni, Sandro, Giuliani, Francesco, Petrelli, Fausto, D’Alessio, Andrea, Gasparini, Giampietro, De Braud, Filippo, Santoro, Armando, Labianca, Roberto, Falanga, Anna
Published in Haematologica (2020)