Expression of genes involved in DNA repair and cell cycle checkpoint pathways in Triple Negative compared to Luminal A Breast Cancer: a molecular characterization

by Ganzinelli Monica, Ribeiro Enilze, Bertoni Ramona, Bazzola Letizia, Andreis Daniele, Bottini Alberto, Giardini Roberto, Rossi Camillo, Damia Giovanna, Generali Daniele
Published 2012-04-01

Expression of genes involved in DNA repair and cell cycle checkpoint pathways in Triple Negative compared to Luminal A Breast Cancer: a molecular characterization

by Ganzinelli, Monica, Ribeiro, Enilze, Bertoni, Ramona, Bazzola, Letizia, Andreis, Daniele, Bottini, Alberto, Giardini, Roberto, Rossi, Camillo, Damia, Giovanna, Generali, Daniele
Published 2012

Updates on the CDK4/6 Inhibitory Strategy and Combinations in Breast Cancer

by Sobhani, Navid, D’Angelo, Alberto, Pittacolo, Matteo, Roviello, Giandomenico, Miccoli, Anna, Corona, Silvia Paola, Bernocchi, Ottavia, Generali, Daniele, Otto, Tobias
Published in Cells (2019)

Targeting the androgenic pathway in elderly patients with castration-resistant prostate cancer: A meta-analysis of randomized trials

by Roviello, Giandomenico, Cappelletti, Maria Rosa, Zanotti, Laura, Gobbi, Angela, Senti, Chiara, Bottini, Alberto, Ravelli, Andrea, Bonetta, Alberto, Paganini, Giovanni, Generali, Daniele
Published in Medicine (Baltimore) (2016)

Association between ramucirumab-related hypertension and response to treatment in patients with metastatic gastric cancer

by Roviello, Giandomenico, Corona, Silvia Paola, Multari, Andrea Giovanni, Paganini, Giovanni, Chiriacò, Giorgio, Conca, Raffaele, Petrioli, Roberto, Generali, Daniele, Rosellini, Pietro, Aieta, Michele
Published in Oncotarget (2018)

Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells

by Cretella, Daniele, Fumarola, Claudia, Bonelli, Mara, Alfieri, Roberta, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Galetti, Maricla, Generali, Daniele, Petronini, Pier Giorgio
Published in Sci Rep (2019)

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition

by Di Modica, Martina, Sfondrini, Lucia, Regondi, Viola, Varchetta, Stefania, Oliviero, Barbara, Mariani, Gabriella, Bianchi, Giulia Valeria, Generali, Daniele, Balsari, Andrea, Triulzi, Tiziana, Tagliabue, Elda
Published in Oncotarget (2015)

The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells

by Cretella, Daniele, Ravelli, Andrea, Fumarola, Claudia, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Alfieri, Roberta, Biondi, Alessandra, Generali, Daniele, Bonelli, Mara, Petronini, Pier Giorgio
Published in J Exp Clin Cancer Res (2018)

Tumour infiltrating lymphocytes and immune-related genes as predictors of outcome in pancreatic adenocarcinoma

by D’Angelo, Alberto, Sobhani, Navid, Roviello, Giandomenico, Bagby, Stefan, Bonazza, Deborah, Bottin, Cristina, Giudici, Fabiola, Zanconati, Fabrizio, De Manzini, Nicolo, Guglielmi, Alessandra, Generali, Daniele
Published in PLoS One (2019)

Tumor Type Agnostic Therapy Carrying BRAF Mutation: Case Reports and Review of Literature

by Bernocchi, Ottavia, Sirico, Marianna, Corona, Silvia Paola, Strina, Carla, Milani, Manuela, Cappelletti, Maria Rosa, Ferrero, Giuseppina, Ziglioli, Nicoletta, Cervoni, Valeria, Macchiavelli, Andrea, Roviello, Giandomenico, Generali, Daniele
Published in Pharmaceuticals (Basel) (2021)

Triple Negative Breast Cancers Have a Reduced Expression of DNA Repair Genes

by Ribeiro, Enilze, Ganzinelli, Monica, Andreis, Daniele, Bertoni, Ramona, Giardini, Roberto, Fox, Stephen B., Broggini, Massimo, Bottini, Alberto, Zanoni, Vanessa, Bazzola, Letizia, Foroni, Chiara, Generali, Daniele, Damia, Giovanna
Published 2013

Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit

by Triulzi, Tiziana, Regondi, Viola, De Cecco, Loris, Cappelletti, Maria Rosa, Di Modica, Martina, Paolini, Biagio, Lollini, Pier Luigi, Di Cosimo, Serena, Sfondrini, Lucia, Generali, Daniele, Tagliabue, Elda
Published in Br J Cancer (2018)

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study

by Corona, Silvia P., Giudici, Fabiola, Jerusalem, Guy, Ciruelos, Eva, Strina, Carla, Sirico, Marianna, Bernocchi, Ottavia, Milani, Manuela, Dester, Martina, Ziglioli, Nicoletta, Barbieri, Giuseppina, Cervoni, Valeria, Montemurro, Filippo, Generali, Daniele
Published in Oncotarget (2020)

The G-protein Coupled Receptor CLR is Up-regulated in an Autocrine Loop with Adrenomedullin in Clear Cell Renal Cell Carcinoma and Associated with Poor Prognosis

by Nikitenko, Leonid L., Leek, Russell, Henderson, Stephen, Pillay, Nischalan, Turley, Helen, Generali, Daniele, Gunningham, Sarah, Morrin, Helen R., Pellagatti, Andrea, Rees, Margaret C.P., Harris, Adrian L., Fox, Stephen B.
Published 2013

The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to pri...

by Fox, Stephen B, Generali, Daniele, Berruti, Alfredo, Brizzi, Maria P, Campo, Leticia, Bonardi, Simone, Bersiga, Alessandra, Allevi, Giovanni, Milani, Manuela, Aguggini, Sergio, Mele, Teresa, Dogliotti, Luigi, Bottini, Alberto, Harris, Adrian L
Published 2011

Platinum sensitivity and DNA repair in a recently established panel of patient-derived ovarian carcinoma xenografts

by Guffanti, Federica, Fratelli, Maddalena, Ganzinelli, Monica, Bolis, Marco, Ricci, Francesca, Bizzaro, Francesca, Chilà, Rosaria, Sina, Federica Paola, Fruscio, Robert, Lupia, Michela, Cavallaro, Ugo, Cappelletti, Maria Rosa, Generali, Daniele, Giavazzi, Raffaella, Damia, Giovanna
Published in Oncotarget (2018)

Immune microenvironment and intrinsic subtyping in hormone receptor-positive/HER2-negative breast cancer

by Griguolo, Gaia, Dieci, Maria Vittoria, Paré, Laia, Miglietta, Federica, Generali, Daniele Giulio, Frassoldati, Antonio, Cavanna, Luigi, Bisagni, Giancarlo, Piacentini, Federico, Tagliafico, Enrico, Cagossi, Katia, Ficarra, Guido, Prat, Aleix, Conte, Pierfranco, Guarneri, Valentina
Published in NPJ Breast Cancer (2021)

Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer

by Nafi, Siti Norasikin Mohd, Generali, Daniele, Kramer-Marek, Gabriela, Gijsen, Merel, Strina, Carla, Cappelletti, Mariarosa, Andreis, Daniele, Haider, Syed, Li, Ji-Liang, Bridges, Esther, Capala, Jacek, Ioannis, Roxanis, Harris, Adrian L, Kong, Anthony
Published 2014

Whole-transcriptome analysis links trastuzumab sensitivity of breast tumors to both HER2 dependence and immune cell infiltration

by Triulzi, Tiziana, De Cecco, Loris, Sandri, Marco, Prat, Aleix, Giussani, Marta, Paolini, Biagio, Carcangiu, Marialuisa L., Canevari, Silvana, Bottini, Alberto, Balsari, Andrea, Menard, Sylvie, Generali, Daniele, Campiglio, Manuela, Di Cosimo, Serena, Tagliabue, Elda
Published in Oncotarget (2015)

Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study

by Alborelli, Ilaria, Generali, Daniele, Jermann, Philip, Cappelletti, Maria Rosa, Ferrero, Giuseppina, Scaggiante, Bruna, Bortul, Marina, Zanconati, Fabrizio, Nicolet, Stefan, Haegele, Jasmin, Bubendorf, Lukas, Aceto, Nicola, Scaltriti, Maurizio, Mucci, Giuseppe, Quagliata, Luca, Novelli, Giuseppe
Published in Cell Death Dis (2019)